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Assay Detail

CHEMBL3380223

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Fe-SOD in Trypanosoma cruzi epimastigote
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model.
Olmo F, Guardia JJ, Marin C, Messouri I, Rosales MJ, Urbanová K, Chayboun I, Chahboun R, Alvarez-Manzaneda EJ, Sánchez-Moreno M.
Eur J Med Chem (2015) 89 : 683 -690
PubMed 25462275 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.37 4.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3355357 1 4.38
CHEMBL3355358 1 4.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3355357 IC50 = 42100.0 nM 4.38
CHEMBL3355358 IC50 = 43900.0 nM 4.36