Assay Detail
Functional
CHEMBL3381652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human K562 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Blue assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358614 | — | — | 1 | 5.52 |
| CHEMBL3358613 | — | — | 1 | 5.52 |
| CHEMBL3358612 | — | — | 1 | 5.52 |
| CHEMBL3358611 | — | — | 1 | 5.52 |
| CHEMBL3358610 | — | — | 1 | 5.52 |
| CHEMBL3358608 | — | — | 1 | 5.52 |
| CHEMBL3358598 | — | — | 1 | 5.52 |
| CHEMBL3358596 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358614 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358613 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358612 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358611 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358610 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358608 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358598 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3358596 | — | IC50 | = | 3000.0 | nM | 5.52 |