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Assay Detail

CHEMBL3381653

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MV4-11
Confidence 1 — Organism
Curated By Autocuration

Target

MV4-11 (CHEMBL613835)
Type CELL-LINE
Organism Homo sapiens

Publication

Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Cumaraswamy AA, Lewis AM, Geletu M, Todic A, Diaz DB, Cheng XR, Brown CE, Laister RC, Muench D, Kerman K, Grimes HL, Minden MD, Gunning PT.
ACS Med Chem Lett (2014) 5 : 1202 -1206
PubMed 25419444 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3358611 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3358611 IC50 = 3000.0 nM 5.52