Assay Detail
Binding
CHEMBL3381675
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Binding affinity to Pseudomonas aeruginosa LecA by ITC method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
PA-I galactophilic lectin (CHEMBL3351196) ↗| Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) |
Publication
Antiadhesive properties of glycoclusters against Pseudomonas aeruginosa lung infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.20 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358626 | — | — | 1 | 6.75 |
| CHEMBL467773 | — | — | 1 | 4.70 |
| CHEMBL442951 | — | — | 1 | 4.16 |
| CHEMBL3358629 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358626 | — | Kd | = | 176.0 | nM | 6.75 |
| CHEMBL467773 | — | Kd | = | 20000.0 | nM | 4.70 |
| CHEMBL442951 | — | Kd | = | 70000.0 | nM | 4.16 |
| CHEMBL3358629 | — | Kd | = | 150000.0 | nM | - |