Assay Detail
Functional
CHEMBL3383124
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Cytotoxicity against human A549 cells assessed as growth inhibition after 120 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of in vitro antimycobacterial activity of novel 1H-benzo[d]imidazole derivatives and analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.94 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358763 | — | — | 1 | 4.96 |
| CHEMBL3358767 | — | — | 1 | 4.96 |
| CHEMBL3358766 | — | — | 1 | 4.95 |
| CHEMBL3358764 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358763 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL3358767 | — | IC50 | = | 11050.0 | nM | 4.96 |
| CHEMBL3358766 | — | IC50 | = | 11150.0 | nM | 4.95 |
| CHEMBL3358764 | — | IC50 | = | 13360.0 | nM | 4.87 |