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Assay Detail

CHEMBL3383852

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Functional
Growth inhibition of human HT-29 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Borrelidin B: isolation, biological activity, and implications for nitrile biosynthesis.
Schulze CJ, Bray WM, Loganzo F, Lam MH, Szal T, Villalobos A, Koehn FE, Linington RG.
J Nat Prod (2014) 77 : 2570 -2574
PubMed 25393949 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.87 6.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL70590 BORRELIDIN 1 6.04
CHEMBL3355648 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL70590 BORRELIDIN IC50 = 920.0 nM 6.04
CHEMBL3355648 IC50 = 2000.0 nM 5.70