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Assay Detail

CHEMBL3384007

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Dengue virus 3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism dengue virus type 3
Confidence 1 — Organism
Curated By Autocuration

Target

dengue virus type 3 (CHEMBL612717)
Type ORGANISM
Organism dengue virus type 3

Publication

A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses.
Bhakat S, Karubiu W, Jayaprakash V, Soliman ME.
Eur J Med Chem (2014) 87 : 677 -702
PubMed 25305334 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.56 5.61

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1877532 1 5.61
CHEMBL1535689 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1877532 EC50 = 2430.0 nM 5.61
CHEMBL1535689 EC50 = 3080.0 nM 5.51