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Assay Detail

CHEMBL3384061

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC8 (unknown origin) after 15 mins by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone deacetylase 8 (CHEMBL3192)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.
Sodji Q, Patil V, Jain S, Kornacki JR, Mrksich M, Tekwani BL, Oyelere AK.
Bioorg Med Chem Lett (2014) 24 : 4826 -4830
PubMed 25240614 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2170177 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2170177 IC50 = 10.0 nM 8.00