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Assay Detail

CHEMBL3384879

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Physicochemical
Antioxidant activity assessed as DPPH free radical scavenging activity after 60 mins by spectrophotometry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

PASS-assisted design, synthesis and antioxidant evaluation of new butylated hydroxytoluene derivatives.
Ariffin A, Rahman NA, Yehye WA, Alhadi AA, Kadir FA.
Eur J Med Chem (2014) 87 : 564 -577
PubMed 25299680 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 4.13 4.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3344053 1 4.29
CHEMBL3344052 1 4.28
CHEMBL196 ASCORBIC ACID 4.0 1 4.17
CHEMBL3344055 1 4.12
CHEMBL3344054 1 4.04
CHEMBL3344057 1 4.03
CHEMBL3344051 1 4.01
CHEMBL146 BUTYLATED HYDROXYTOLUENE 2.0 1 -
CHEMBL3344056 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3344053 IC50 = 50930.0 nM 4.29
CHEMBL3344052 IC50 = 52030.0 nM 4.28
CHEMBL196 ASCORBIC ACID IC50 = 67770.0 nM 4.17
CHEMBL3344055 IC50 = 76800.0 nM 4.12
CHEMBL3344054 IC50 = 90770.0 nM 4.04
CHEMBL3344057 IC50 = 92690.0 nM 4.03
CHEMBL3344051 IC50 = 96730.0 nM 4.01
CHEMBL146 BUTYLATED HYDROXYTOLUENE IC50 > 100000.0 nM -
CHEMBL3344056 IC50 > 100000.0 nM -