Assay Detail
Physicochemical
CHEMBL3384881
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity assessed as inhibition of lipid peroxidation after 1 hr by TBARS assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PASS-assisted design, synthesis and antioxidant evaluation of new butylated hydroxytoluene derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.75 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3344057 | — | — | 1 | 5.54 |
| CHEMBL47 | ALPHA-TOCOPHEROL | — | 1 | 5.25 |
| CHEMBL3344055 | — | — | 1 | 5.10 |
| CHEMBL3344054 | — | — | 1 | 4.88 |
| CHEMBL3344053 | — | — | 1 | 4.52 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 4.44 |
| CHEMBL3344051 | — | — | 1 | 4.41 |
| CHEMBL3344056 | — | — | 1 | 4.41 |
| CHEMBL3344052 | — | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3344057 | — | IC50 | = | 2850.0 | nM | 5.54 |
| CHEMBL47 | ALPHA-TOCOPHEROL | IC50 | = | 5630.0 | nM | 5.25 |
| CHEMBL3344055 | — | IC50 | = | 7980.0 | nM | 5.10 |
| CHEMBL3344054 | — | IC50 | = | 13170.0 | nM | 4.88 |
| CHEMBL3344053 | — | IC50 | = | 30100.0 | nM | 4.52 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | IC50 | = | 36670.0 | nM | 4.44 |
| CHEMBL3344051 | — | IC50 | = | 38840.0 | nM | 4.41 |
| CHEMBL3344056 | — | IC50 | = | 38870.0 | nM | 4.41 |
| CHEMBL3344052 | — | IC50 | = | 60530.0 | nM | 4.22 |