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Assay Detail

CHEMBL3385406

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to SUR1 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

ATP-binding cassette sub-family C member 8 (CHEMBL2071)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel sulfonyl(thio)urea derivatives act efficiently both as insulin secretagogues and as insulinomimetic compounds.
Mascarello A, Frederico MJ, Castro AJ, Mendes CP, Dutra MF, Woehl VM, Yunes RA, Mena Barreto Silva FR, Nunes RJ.
Eur J Med Chem (2014) 86 : 491 -501
PubMed 25203779 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 9.05 9.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3330880 1 9.42
CHEMBL3330879 1 8.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3330880 Kd = 0.38 nM 9.42
CHEMBL3330879 Kd = 2.08 nM 8.68