Assay Detail
Binding
CHEMBL3385517
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Binding affinity to AT1 receptor (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Saralasin and Sarile Are AT2 Receptor Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.43 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL938 | SARALASIN | 4.0 | 1 | 9.66 |
| CHEMBL404594 | — | — | 1 | 9.19 |
| CHEMBL2086892 | — | — | 1 | - |
| CHEMBL189568 | BULOXIBUTID | 0.5 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL938 | SARALASIN | Ki | = | 0.22 | nM | 9.66 |
| CHEMBL404594 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL2086892 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL189568 | BULOXIBUTID | Ki | > | 10000.0 | nM | - |