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Assay Detail

CHEMBL3385666

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Binding
Inhibition of Staphylococcus aureus enoyl ACP reductase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (CHEMBL3994)
Type SINGLE PROTEIN
Organism Staphylococcus aureus

Publication

Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus.
Wang H, Lu Y, Liu L, Kim SW, Hooker JM, Fowler JS, Tonge PJ.
Eur J Med Chem (2014) 88 : 66 -73
PubMed 25217335 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 11.00 11.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3360252 1 11.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3360252 Ki = 0.01 nM 11.00