Assay Detail
ADMET
CHEMBL3385706
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Toxicity against Saccharomyces cerevisiae AD1-8u(-) overexpressing CaMdr1p
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Saccharomyces cerevisiae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Jatrophanes from Euphorbia squamosa as potent inhibitors of Candida albicans multidrug transporters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.87 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3354232 | — | — | 1 | 5.46 |
| CHEMBL3354234 | — | — | 1 | 4.60 |
| CHEMBL3354231 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3354232 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL3354234 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL3354231 | — | IC50 | = | 28300.0 | nM | 4.55 |