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Assay Detail

CHEMBL3386414

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Functional
Antiproliferative activity against human HT-29 cells by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and antiproliferative evaluation of 2-hydroxylated (E)-stilbenes.
Zhang Y, Shen M, Cui S, Hou T.
Bioorg Med Chem Lett (2014) 24 : 5470 -5472
PubMed 25455486 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 4.71 5.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3354309 1 5.02
CHEMBL507494 1 5.01
CHEMBL3354307 1 5.00
CHEMBL3354311 1 4.90
CHEMBL3354308 1 4.88
CHEMBL3354299 1 4.84
CHEMBL3354310 1 4.73
CHEMBL3354298 1 4.64
CHEMBL3354302 1 4.58
CHEMBL206049 1 4.58
CHEMBL3354306 1 4.57
CHEMBL3354300 1 4.47
CHEMBL165 RESVERATROL 3.0 1 4.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3354309 IC50 = 9500.0 nM 5.02
CHEMBL507494 IC50 = 9700.0 nM 5.01
CHEMBL3354307 IC50 = 10000.0 nM 5.00
CHEMBL3354311 IC50 = 12600.0 nM 4.90
CHEMBL3354308 IC50 = 13300.0 nM 4.88
CHEMBL3354299 IC50 = 14400.0 nM 4.84
CHEMBL3354310 IC50 = 18500.0 nM 4.73
CHEMBL3354298 IC50 = 22900.0 nM 4.64
CHEMBL3354302 IC50 = 26200.0 nM 4.58
CHEMBL206049 IC50 = 26200.0 nM 4.58
CHEMBL3354306 IC50 = 26700.0 nM 4.57
CHEMBL3354300 IC50 = 33500.0 nM 4.47
CHEMBL165 RESVERATROL IC50 = 87200.0 nM 4.06