Assay Detail
Binding
CHEMBL3386523
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Inhibition of PFKFB3 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (CHEMBL2331053) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
An update on therapeutic opportunities offered by cancer glycolytic metabolism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.48 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3105836 | — | — | 1 | 6.68 |
| CHEMBL3105839 | — | — | 1 | 5.13 |
| CHEMBL3105848 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3105836 | — | IC50 | = | 207.0 | nM | 6.68 |
| CHEMBL3105839 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL3105848 | — | IC50 | = | 22900.0 | nM | 4.64 |