Assay Detail
Functional
CHEMBL3386564
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimicrobial activity against chloroquine-resistant Plasmodium falciparum Dd2 assessed as growth inhibition after 3 days by HRP2-based ELISA
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.87 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2164256 | — | — | 1 | 6.60 |
| CHEMBL3341763 | — | — | 1 | 6.52 |
| CHEMBL3342262 | — | — | 1 | 5.96 |
| CHEMBL3342260 | — | — | 1 | 5.92 |
| CHEMBL3342258 | — | — | 1 | 5.55 |
| CHEMBL3342259 | — | — | 1 | 5.44 |
| CHEMBL3342261 | — | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2164256 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL3341763 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL3342262 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL3342260 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3342258 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL3342259 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL3342261 | — | IC50 | = | 8100.0 | nM | 5.09 |