Assay Detail
Functional
CHEMBL3386565
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Antimicrobial activity against multidrug-resistant Plasmodium falciparum FCR3 assessed as growth inhibition after 3 days by HRP2-based ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.35 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2164256 | — | — | 1 | 6.42 |
| CHEMBL3342262 | — | — | 1 | 6.39 |
| CHEMBL3341763 | — | — | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2164256 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL3342262 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL3341763 | — | IC50 | = | 570.0 | nM | 6.24 |