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Assay Detail

CHEMBL3387183

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Binding
Agonist activity at human NPFF2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neuropeptide FF receptor 2 (CHEMBL5952)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors.
Journigan VB, Mésangeau C, Vyas N, Eans SO, Cutler SJ, McLaughlin JP, Mollereau C, McCurdy CR.
J Med Chem (2014) 57 : 8903 -8927
PubMed 25268943 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.57 8.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3360830 1 8.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3360830 EC50 = 2.7 nM 8.57