Assay Detail
Binding
CHEMBL3387285
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rabbit erythrocyte SAHase using S-adenosyl-L-homocysteine as substrate assessed as L-homocysteine formation incubated for 5 mins prior to substrate addition measured after 1 hr
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antiviral activities of 3-deaza-3-fluoroaristeromycin and its 5' analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.97 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3290663 | — | — | 1 | 8.24 |
| CHEMBL3357216 | — | — | 1 | 8.05 |
| CHEMBL154745 | — | — | 1 | 8.03 |
| CHEMBL3357215 | — | — | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3290663 | — | IC50 | = | 5.8 | nM | 8.24 |
| CHEMBL3357216 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL154745 | — | IC50 | = | 9.3 | nM | 8.03 |
| CHEMBL3357215 | — | IC50 | = | 29.0 | nM | 7.54 |