Assay Detail
Functional
CHEMBL3387292
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Antiviral activity against human cytomegalovirus infected in HFF cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antiviral activities of 3-deaza-3-fluoroaristeromycin and its 5' analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.83 | 5.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3357216 | — | — | 1 | 5.83 |
| CHEMBL3290663 | — | — | 1 | - |
| CHEMBL3357215 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3357216 | — | IC50 | = | 1490.0 | nM | 5.83 |
| CHEMBL3290663 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL3357215 | — | IC50 | > | 60000.0 | nM | - |