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Assay Detail

CHEMBL3387304

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Tacaribe virus infected in African green monkey Vero 76 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mammarenavirus tacaribeense
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Tacaribe virus (CHEMBL613131)
Type ORGANISM
Organism Mammarenavirus tacaribeense

Publication

Synthesis and antiviral activities of 3-deaza-3-fluoroaristeromycin and its 5' analogues.
Chen Q, Liu C, Komazin G, Bowlin TL, Schneller SW.
Bioorg Med Chem (2014) 22 : 6961 -6964
PubMed 25456389 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.02 5.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3357216 1 5.19
CHEMBL3357215 1 4.85
CHEMBL3290663 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3357216 IC50 = 6400.0 nM 5.19
CHEMBL3357215 IC50 = 14000.0 nM 4.85
CHEMBL3290663 IC50 > 300000.0 nM -