Assay Detail
Binding
CHEMBL3387541
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Inhibition of full-length HSP90 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.53 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3360305 | — | — | 1 | 9.00 |
| CHEMBL3360303 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3360305 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3360303 | — | IC50 | = | 900.0 | nM | 6.05 |