Assay Detail
Binding
CHEMBL3388377
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of the thujaplicins for inhibition of human tyrosinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.16 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222541 | — | — | 1 | 7.16 |
| CHEMBL222021 | PROTOCATECHUALDEHYDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222541 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL222021 | PROTOCATECHUALDEHYDE | IC50 | = | 0.4 | ug.mL-1 | - |