Assay Detail
Functional
CHEMBL3389771
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Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth at 10 to 60 uM after 4 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Canthin-6-one displays antiproliferative activity and causes accumulation of cancer cells in the G2/M phase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.82 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL156897 | CANTHIN-6-ONE | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL156897 | CANTHIN-6-ONE | EC50 | = | 15000.0 | nM | 4.82 |