Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3389920

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of integrin alphavbeta6 (unknown origin) by Merck binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-V/beta-6 (CHEMBL2111416)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Structure Activity Relationships of αv Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents.
Adams J, Anderson EC, Blackham EE, Chiu YW, Clarke T, Eccles N, Gill LA, Haye JJ, Haywood HT, Hoenig CR, Kausas M, Le J, Russell HL, Smedley C, Tipping WJ, Tongue T, Wood CC, Yeung J, Rowedder JE, Fray MJ, McInally T, Macdonald SJ.
ACS Med Chem Lett (2014) 5 : 1207 -1212
PubMed 25408832 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.40 10.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL267434 1 10.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL267434 IC50 = 0.04 nM 10.40