Assay Detail
Binding
CHEMBL3390252
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]I-AB-MECA from human adenosine A3 receptor expressed in CHO cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-Based Design of Reactive Nucleosides for Site-Specific Modification of the A2A Adenosine Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.23 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3335526 | — | — | 1 | 6.77 |
| CHEMBL3335523 | — | — | 1 | 6.68 |
| CHEMBL331372 | CGS-21680 | — | 1 | 6.24 |
| CHEMBL3335524 | — | — | 1 | 5.74 |
| CHEMBL3335525 | — | — | 1 | 5.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3335526 | — | Ki | = | 171.0 | nM | 6.77 |
| CHEMBL3335523 | — | Ki | = | 207.0 | nM | 6.68 |
| CHEMBL331372 | CGS-21680 | Ki | = | 570.0 | nM | 6.24 |
| CHEMBL3335524 | — | Ki | = | 1810.0 | nM | 5.74 |
| CHEMBL3335525 | — | Ki | = | 1960.0 | nM | 5.71 |