Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3390780

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to full-length His-tagged STAT5B (unknown origin) by surface plasmon resonance assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Signal transducer and activator of transcription 5B (CHEMBL5817)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Cumaraswamy AA, Lewis AM, Geletu M, Todic A, Diaz DB, Cheng XR, Brown CE, Laister RC, Muench D, Kerman K, Grimes HL, Minden MD, Gunning PT.
ACS Med Chem Lett (2014) 5 : 1202 -1206
PubMed 25419444 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.38 7.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3358611 1 7.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3358611 Kd = 42.0 nM 7.38