Assay Detail
Binding
CHEMBL3391002
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Binding affinity to human MDMX after 30 mins by surface plasmon resonance spectroscopy
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.76 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3347578 | — | — | 1 | 8.40 |
| CHEMBL502723 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3347578 | — | Kd | = | 4.0 | nM | 8.40 |
| CHEMBL502723 | — | Kd | = | 77.0 | nM | 7.11 |