Assay Detail
Functional
CHEMBL3391105
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Cytotoxicity against human MCF7 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.61 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096450 | — | — | 1 | 7.77 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 7.50 |
| CHEMBL486273 | — | — | 1 | 6.96 |
| CHEMBL1098730 | — | — | 1 | 6.33 |
| CHEMBL3347552 | — | — | 1 | 6.05 |
| CHEMBL96581 | — | — | 1 | 5.02 |
| CHEMBL194094 | — | — | 1 | - |
| CHEMBL3347553 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096450 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL486273 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL1098730 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL3347552 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL96581 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL194094 | — | IC50 | > | 2500.0 | nM | - |
| CHEMBL3347553 | — | IC50 | > | 2500.0 | nM | - |