Assay Detail
Binding
CHEMBL3391489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of yeast Sir2p HAD activity using [3H]-acetylated histone H4 as substrate assessed as release of free [3H]-acetate after 16 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of second generation epigenetic agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.22 | 4.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86537 | SPLITOMICIN | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86537 | SPLITOMICIN | IC50 | = | 60000.0 | nM | 4.22 |