Assay Detail
Binding
CHEMBL3395012
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Inhibition of rat nNOS
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based design of bacterial nitric oxide synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.57 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2326360 | — | — | 1 | 7.28 |
| CHEMBL1615292 | — | — | 1 | 7.07 |
| CHEMBL3394386 | — | — | 1 | 6.71 |
| CHEMBL3394388 | — | — | 1 | 6.66 |
| CHEMBL2326358 | — | — | 1 | 6.27 |
| CHEMBL3128242 | — | — | 1 | 6.09 |
| CHEMBL3394387 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2326360 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL1615292 | — | Ki | = | 85.0 | nM | 7.07 |
| CHEMBL3394386 | — | Ki | = | 196.0 | nM | 6.71 |
| CHEMBL3394388 | — | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL2326358 | — | Ki | = | 540.0 | nM | 6.27 |
| CHEMBL3128242 | — | Ki | = | 819.0 | nM | 6.09 |
| CHEMBL3394387 | — | Ki | = | 1267.0 | nM | 5.90 |