Assay Detail

CHEMBL3395079

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Binding

Reversible competitive inhibition of Sprague-Dawley rat liver AMPK using 33P-ATP as substrate after 30 mins

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Rana S, Blowers EC, Natarajan A.
J Med Chem (2015) 58 : 2 -29
PubMed 25122135 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	6.96	6.96

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL478629	DORSOMORPHIN	—	1	6.96

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL478629	DORSOMORPHIN	Ki	=	109.0	nM	6.96