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Assay Detail

CHEMBL3395273

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to NT-647-NHS fluorescent dye-labeled dengue virus 3 NS2B-NS3 serine protease incubated for 10 mins by microscale thermophoresis method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism dengue virus type 3
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: inhibition kinetics and docking studies.
de Sousa LR, Wu H, Nebo L, Fernandes JB, da Silva MF, Kiefer W, Kanitz M, Bodem J, Diederich WE, Schirmeister T, Vieira PC.
Bioorg Med Chem (2015) 23 : 466 -470
PubMed 25564380 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1173475 QUERCETIN DIHYDRATE 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1173475 QUERCETIN DIHYDRATE Kd = 20000.0 nM 4.70