Assay Detail
Binding
CHEMBL3395897
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Inhibition of JNK2 (unknown origin) by time-resolved fluorescence assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of c-Jun N-terminal kinases: an update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.99 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1725279 | SP-600125 | — | 1 | 7.40 |
| CHEMBL3220466 | — | — | 1 | 7.30 |
| CHEMBL3393595 | — | — | 1 | 7.23 |
| CHEMBL1761554 | — | — | 1 | 7.05 |
| CHEMBL585951 | — | — | 1 | 7.00 |
| CHEMBL3393596 | — | — | 1 | 6.91 |
| CHEMBL2144409 | — | — | 1 | 6.55 |
| CHEMBL3393597 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1725279 | SP-600125 | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3220466 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3393595 | — | IC50 | = | 59.0 | nM | 7.23 |
| CHEMBL1761554 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL585951 | — | IC50 | = | 99.0 | nM | 7.00 |
| CHEMBL3393596 | — | IC50 | = | 123.0 | nM | 6.91 |
| CHEMBL2144409 | — | IC50 | = | 283.0 | nM | 6.55 |
| CHEMBL3393597 | — | IC50 | = | 339.0 | nM | 6.47 |