Assay Detail
Binding
CHEMBL3398781
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tissue kallikrein (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.06 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3398612 | — | — | 1 | 6.19 |
| CHEMBL3398644 | — | — | 1 | 5.92 |
| CHEMBL3398642 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3398612 | — | Ki | = | 650.0 | nM | 6.19 |
| CHEMBL3398644 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL3398642 | — | Ki | > | 30000.0 | nM | - |