Assay Detail
Binding
CHEMBL3399062
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MLL (unknown origin) by HMT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase 2A (CHEMBL1293299) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SAH derived potent and selective EZH2 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.19 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418052 | S-ADENOSYLHOMOCYSTEINE | — | 1 | 5.64 |
| CHEMBL3397332 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418052 | S-ADENOSYLHOMOCYSTEINE | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3397332 | — | IC50 | = | 18500.0 | nM | 4.73 |