Assay Detail
Functional
CHEMBL3399490
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Antimicrobial activity against chloroquine-sensitive Plasmodium falciparum 3D7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Reemergence of chloroquine (CQ) analogs as multi-targeting antimalarial agents: a review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.99 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 7.52 |
| CHEMBL3219153 | — | — | 1 | 7.10 |
| CHEMBL506 | PRIMAQUINE | 4.0 | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3219153 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL506 | PRIMAQUINE | IC50 | = | 460.0 | nM | 6.34 |