Assay Detail
Binding
CHEMBL3399576
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIF-1alpha in human Hep3B cells assessed as decrease in VEGF level after 20 hrs by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Hep 3B2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bioactive benzofuran derivatives: moracins A-Z in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.97 | 4.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL380456 | (+/-)-MORACIN P | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL380456 | (+/-)-MORACIN P | IC50 | = | 10600.0 | nM | 4.97 |