Assay Detail
Functional
CHEMBL3399754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HCV genotype 2a infected in human HuH7 cells by replicon based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.64 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3398124 | — | — | 1 | 5.64 |
| CHEMBL3398125 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3398124 | — | EC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3398125 | — | EC50 | > | 88000.0 | nM | - |