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Assay Detail

CHEMBL3404385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Irreversible inhibition of rat hormone sensitive lipase assessed as relative residual activity by kinetic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Hormone-sensitive lipase (CHEMBL5582)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Rat hormone sensitive lipase inhibition by cyclipostins and their analogs.
Vasilieva E, Dutta S, Malla RK, Martin BP, Spilling CD, Dupureur CM.
Bioorg Med Chem (2015) 23 : 944 -952
PubMed 25678014 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3401162 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3401162 Ki = 40.0 nM 7.40