Assay Detail
Functional
CHEMBL3404672
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Antiproliferative activity against human HepG2 cells assessed cell survival after 24 hrs by alamarBlue assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Indirubin 3'-(O-oxiran-2-ylmethyl)oxime: a novel anticancer agent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.42 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3401494 | — | — | 1 | 5.77 |
| CHEMBL1276317 | — | — | 1 | 5.68 |
| CHEMBL216543 | — | — | 1 | 4.82 |
| CHEMBL1276127 | INDIRUBIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3401494 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1276317 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL216543 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1276127 | INDIRUBIN | IC50 | - | — | - |