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Assay Detail

CHEMBL3404677

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Functional
Cytotoxicity against human HepG2 cells assessed cell death after 72 hrs by alamarBlue assay relative to control
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Indirubin 3'-(O-oxiran-2-ylmethyl)oxime: a novel anticancer agent.
Ichimaru Y, Saito H, Uchiyama T, Metori K, Tabata K, Suzuki T, Miyairi S.
Bioorg Med Chem Lett (2015) 25 : 1403 -1406
PubMed 25765906 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.60 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3401494 1 5.64
CHEMBL1276317 1 5.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3401494 IC50 = 2300.0 nM 5.64
CHEMBL1276317 IC50 = 2800.0 nM 5.55