Assay Detail
Binding
CHEMBL3404793
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Inhibition of FABP4 (unknown origin) relative to linoleic acid
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.33 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3400905 | — | — | 1 | 6.64 |
| CHEMBL3400157 | — | — | 1 | 6.35 |
| CHEMBL267476 | LINOLEIC ACID | 2.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3400905 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL3400157 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL267476 | LINOLEIC ACID | IC50 | = | 1000.0 | nM | 6.00 |