Assay Detail
Binding
CHEMBL3404962
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.00 | 9.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3403631 | — | — | 1 | 9.08 |
| CHEMBL3403619 | — | — | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3403631 | — | EC50 | = | 0.83 | nM | 9.08 |
| CHEMBL3403619 | — | EC50 | = | 1.2 | nM | 8.92 |