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Assay Detail

CHEMBL3405907

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Yellow fever virus
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Yellow fever virus
Confidence 1 — Organism
Curated By Autocuration

Target

Yellow fever virus (CHEMBL613731)
Type ORGANISM
Organism Yellow fever virus

Publication

Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors.
Jadav SS, Kaptein S, Timiri A, De Burghgraeve T, Badavath VN, Ganesan R, Sinha BN, Neyts J, Leyssen P, Jayaprakash V.
Bioorg Med Chem Lett (2015) 25 : 1747 -1752
PubMed 25791449 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.40 4.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL476135 1 4.51
CHEMBL476968 1 4.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL476135 IC50 = 31000.0 nM 4.51
CHEMBL476968 IC50 = 51000.0 nM 4.29