Assay Detail
Binding
CHEMBL3406334
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK1/cyclin B (unknown origin) expressed in baculovirus infected Sf9 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cyclin-dependent kinase 1/cyclin B1 (CHEMBL1907602) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Novel arylazopyrazole inhibitors of cyclin-dependent kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.06 | 5.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3402056 | — | — | 1 | 5.88 |
| CHEMBL3402060 | — | — | 1 | 4.95 |
| CHEMBL215205 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3402056 | — | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL3402060 | — | IC50 | = | 11290.0 | nM | 4.95 |
| CHEMBL215205 | — | IC50 | = | 44000.0 | nM | 4.36 |