Assay Detail
Functional
CHEMBL3411581
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Antiproliferative activity against human HeLa cells after 4 days by Coulter counter method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.04 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1958071 | — | — | 1 | 7.18 |
| CHEMBL3410282 | — | — | 1 | 7.12 |
| CHEMBL289351 | FOSBRETABULIN DISODIUM | 2.0 | 1 | 7.10 |
| CHEMBL1958070 | — | — | 1 | 6.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1958071 | — | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL3410282 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL289351 | FOSBRETABULIN DISODIUM | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL1958070 | — | IC50 | = | 182.0 | nM | 6.74 |