Assay Detail
Binding
CHEMBL3412555
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Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Syntheses of chondroitin sulfate tetrasaccharide structures containing 4,6-disulfate patterns and analysis of their interaction with glycosaminoglycan-binding protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 8.01 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3559508 | — | — | 1 | 8.33 |
| CHEMBL3409457 | — | — | 1 | 8.28 |
| CHEMBL3409454 | — | — | 1 | 8.25 |
| CHEMBL3409455 | — | — | 1 | 8.09 |
| CHEMBL3409453 | — | — | 1 | 7.80 |
| CHEMBL3559507 | — | — | 1 | 7.32 |
| CHEMBL3409451 | — | — | 1 | - |
| CHEMBL3559506 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3559508 | — | Kd | = | 4.7 | nM | 8.33 |
| CHEMBL3409457 | — | Kd | = | 5.2 | nM | 8.28 |
| CHEMBL3409454 | — | Kd | = | 5.6 | nM | 8.25 |
| CHEMBL3409455 | — | Kd | = | 8.2 | nM | 8.09 |
| CHEMBL3409453 | — | Kd | = | 16.0 | nM | 7.80 |
| CHEMBL3559507 | — | Kd | = | 48.0 | nM | 7.32 |
| CHEMBL3409451 | — | Kd | - | — | - | |
| CHEMBL3559506 | — | Kd | - | — | - |