Assay Detail
Physicochemical
CHEMBL3412982
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Antioxidant activity assessed as DPPH scavenging activity after 30 mins by spectrophotometry
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.38 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3410951 | — | — | 1 | 7.52 |
| CHEMBL153 | TROLOX | — | 1 | 7.45 |
| CHEMBL3410953 | — | — | 1 | 7.39 |
| CHEMBL3410957 | — | — | 1 | 7.37 |
| CHEMBL3410952 | — | — | 1 | 7.36 |
| CHEMBL3410955 | — | — | 1 | 7.33 |
| CHEMBL3410956 | — | — | 1 | 7.33 |
| CHEMBL3410954 | — | — | 1 | 7.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3410951 | — | IC50 | = | 30.4 | nM | 7.52 |
| CHEMBL153 | TROLOX | IC50 | = | 35.6 | nM | 7.45 |
| CHEMBL3410953 | — | IC50 | = | 40.7 | nM | 7.39 |
| CHEMBL3410957 | — | IC50 | = | 43.2 | nM | 7.37 |
| CHEMBL3410952 | — | IC50 | = | 44.2 | nM | 7.36 |
| CHEMBL3410955 | — | IC50 | = | 46.9 | nM | 7.33 |
| CHEMBL3410956 | — | IC50 | = | 47.3 | nM | 7.33 |
| CHEMBL3410954 | — | IC50 | = | 48.7 | nM | 7.31 |